Peptide Endotoxin Testing

What Is Endotoxin Testing?

Endotoxins are lipopolysaccharide (LPS) components of the outer membrane of Gram-negative bacteria. If present in injectable products, endotoxins can cause fever, inflammation, and septic shock. Endotoxin testing — typically performed using the Limulus Amebocyte Lysate (LAL) test — detects and quantifies endotoxin levels in a sample.

For research-grade peptides, endotoxin testing is not always included in standard batch release. For partners requiring injectable-grade documentation, endotoxin testing can be arranged as part of the CDMO project agreement.